First, check over what you're putting into the issue - does it have special characters or unusual content in it? (e.g. accented characters, text in a language that you don't usually use, or emojis, for example). Can you create issues without any special content?
Second, can you read the log file and see if there are errors appearing in that at the time at which you click "create"?
Did you remove the post-function before you un-installed script-runner? Depending on the version, you might still be able to remove it, but a post-function that tries to use add-ons that have been removed can easily block transitions from working.
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