Jira Python issue by region

[Pegah Lashgarlou]

Does anyone know how I can narrow down the issues in my project by region/domain? 

I have:

s = jira.search_issues('project="example"', startAt=0, maxResults=0, json_result=True)

how do I narrow it down more to region? tried:

s = jira.search_issues('project="DC Ops" and region="x"', startAt=0, maxResults=0, json_result=True)

but that didn't work.

Thanks in advance!