Hi @Neil Armstrong -- Welcome to the Atlassian Community!
Short answer: not with out-of-the-box Jira Cloud features
Jira's JQL is not a SQL, and so does not have such features. And the reporting does not easily do this type of analysis: essentially looking for the absence of information (i.e. no epics).
What you can try depends upon how often you need this and your willingness to purchase addon products...
Sorry, I do not...we are not using any such reporting addons now other than some dashboard gadgets, and those would not see "there is no data for this feature".
My suggestion would be to look as some of the free (or free to trial) addons to see what generates reports matching what you want: https://marketplace.atlassian.com/