This needs to be approached in two ways, yes the links above will help to remove the trailing signature text, but as the image is HTML encoded (possibly externally), most mail handlers will just extract and add the image.
JEMH does the extra bit you need and allows specifically named files to be ignored, so if you're logo is called 'logo.png' in the page, you could blacklist that from being attached.
<grin> It's a good point - Andy has invested a lot of effort in JEMH and it's well worth it if you want to do anything in the slightest bit clever with email in Jira.
If you don't want to invest in it, then you will need to write your own handler, and I wouldn't expect Andy to help you.
It's good to present a plugin as an easy solution, but this doesn't quite work as an answer asked about JIRA itself. It would be less confusing, and more complete, to provide an answer such as, "JIRA does not provide this capability itself. A marketplace plugin such as JEMH will do this, with the alternative of writing your own mail handler using the JIRA API." The partial answer implied a method, minimally outlined, requiring the OP to ask a followup. The OP is unlikely to know that username "Andy Brook" is the creator of JEMH, and so was pointing to his product as a convenient read-made solution, not offering technical details towards a DIY approach. If amended as suggested, answering with a paid fix may still result in the question going unseen by someone who could offer more technical details on using the API for this purpose. It would be nice if the community would adopt a convention whereby such responsed were instead submitted as comments on the question, leaving "answers" for addressing the question in a JIRA-native/vanilla fashion, at least when context calls for it. I'm sure I'm over thinking this, but I have come upon a wide variety of answers like this that, while somewhat helpful, ultimately obscured the issue and potential solutions.
Goal: I need to create and comment issues using email (https://confluence.atlassian.com/display/JIRA/Creating+Issues+and+Comments+from+Email)
Result:I can create /comment issue from email (its ok)
Problem:I don’t know how to strip signature with logo (see attach) from email
I found a few information here, but I can’t remove logo/image
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