As far as I remember, you are allowed to change everything as long as you do not have conflicts with other projects. The unique identifier of your project is the key and keeping it intact will not even initiate a re-index need. Now, if you are using the proposed key that JIRA suggests when typing a project name, then you will only have inconsistency with your naming convention, but other than that I do not see anything else.
Hope I understood your question and helped
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