If they do not contain data you might want to keep, then yes, absolutely feel free to kill the fields off.
I would check by
Rename all of those fields slightly, changing them to something like External issue id 1, 2, 3, etc, so you can tell the difference
Run a search for "external issue id 1 is not empty", then for 2, then 3 etc. When you get 0 hits, it's perfectly safe to remove it (note that you should check that you can see the projects affected!)
But if not empty? Should I keep them?
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That's a business decision. The question to ask each project owner is if they need the data you find there. If they do not, then you can kill the fields.
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