You can muck with the velocity template that controls that.
In JIRA 4.4.3, edit the atlassian-jira-4.4.3-standalone/atlassian-jira/WEB-INF/classes/templates/plugins/userprofile/details-profile-fragment.vm
Find this section:
#if($groups) <dl> <dt>$i18n.getText('common.words.groups'):</dt> <dd class="description"> #foreach($group in $groups) $textutils.htmlEncode($group)<br/> #end </dd> </dl> #end
Replace $groups with 1==0
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