Can you enforce 2FA for non-managed invited users?

[Andrei]

We have an organization, a verified domain, and claimed accounts. 

We'd also want to invite users from outside of our organization (domain) to access and be part of our Confluence Cloud instance. 

As we'd like access to our data to be as secure as possible, is there a way to enforce them to have 2FA enabled?

- Something like.. if this user doesn't have 2FA enabled AND isn't logged with OAuth(Google, AD, etc), don't allow them to access our instance.

[Administrator]

I have found that on the Jira side, it automatically made a group that had all users in Azure AD. I didn't assign any product to that group with all users (as they are only Jira service desk "customers"). 

Then, I created my other groups which I assigned the licence to for the agents using Jira itself. This gives them access to the back-side of our Service Desk.

However, It seems after a few days I am now having issues with the list of "All Users" which synced automatically. I can see them all listed in the user settings sections as having site access but then, when I head over to the service portal URL from my test user, it says that there is no access to the portal for some reason.. 

Still trying to figure that discrepancy out. Hoping If I mention it here, there may be an answer...