I don't think Confluence has a REST API endpoint for that yet, but you can use the XML-RPC/JSON-RPC API for that. There's a method called "addProfilePicture" that you can use: https://developer.atlassian.com/server/confluence/remote-confluence-methods/#user-management
If you're looking to do so in JIRA, it's a bit different and can be done via the REST API. This was the answer I used when I was trying to figure it out: https://community.atlassian.com/t5/Answers-Developer-Questions/Avatar-upload-with-Jira-5-REST-API/qaq-p/475376
Don't know if this bug still exists but the @mention photos will be missing if you upload via the old RPC API. A reindex will fix it, but not ideal if you're constantly updating profile pictures.
The following REST calls may help you. These calls are private. I'll try them tomorrow, too. Let's see what happens. Or have you already solved it?
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