It's currently impossible to use Two Factor Authentication on cloud instances. However, there's a feature request as you can see on CLOUD-7828 and CLOUD-8442. You can vote and comment on it in order to increase its visibility.
When I asked Atlassian about this, they pointed me to their Implementation of New Features Policy in order to understand how developers team analyse and prioritizes requests.
I have multiple projects that use variations of the same base workflow. The variations depend on the requirements of the project or issue type. The variations mostly come in the form of new statuses ...
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