What I'd like to do is be able to create many issues of a similar type in rapid-fire fashion without touching the mouse. From a UI standpoint, FogBugz get this just right, and I'd like to be able to produce issues with the same amount of ease in JIRA.
Looking at the keyboard shortcut reference, Ctrl-S is said to submit the current form; from greenhopper's Create Card dialog, Ctrl-S does submit the form, but via the "Create and Close" button. I want a keyboard shortcut to trigger the "Create" button, so I can go on in writing out the summary of the next issue, etc.