Editing a page title and clicking 'update' has suddenly started to result in the below error message showing

Additional findings:
- This is affecting wiki pages only; not blog posts
- It's a site-wide issue
- It's only affecting the live environment, not dev
- The URL shown for the error message is the URL that the wiki page should have with the updated title.
Eg:
- Original page title is /spacekey/This+page
- Edit page
- Change page title to This page 1
- Click update
- Page loads with above error message, and URL /spacekey/This+page+1
Anyone seen this before, and now how to resolve it? We're on Confluence v6.4, IE11. We can't use another browser.