After yesterday's update, CMD+S no longer saves pages. Instead, it lets the browser deal with the keyboard shortcut, showing the "Save this page" dialog.
I realize you're trying to be consistent and leave the standard keyboard shortcuts for the browser, but saving an HTML page locally is not a common operation. No-one will complain if you continue to take it over.
CMD+Enter, your new shortcut, is not intuitive, and it's usually used for adding a "small carriage return", a <br/> instead of a <p>.
Please do the right thing and bring back CMD+S.