The default limit of 1024 was too low during startup of Confluence. If the site was accessed immediately after restart, Confluence would report that it could not find resources that were clearly there. After waiting a few minutes, the problem cleated. I suspect this was because some background jobs (maybe indexing?) finished and freed file handles. When I run lsof on the Confluence process id, it usually has about 900 files open.
After doubling the open file limit to 2048, the problem cleared. Is this typical or does it indicate a problem with my installation?
Using Confluence 4.2 on CentOS 5.8