You haven't said what application you are working with here.
If you mean Jira though, you've already had an answer - see https://answers.atlassian.com/questions/247492/can-i-specify-resolution-and-priority-options-for-the-different-issues
For priority, edit the issues
For Resolution, it's a bit more difficult. Reopening the issues will blank it out, assuming your workflow is correctly constructed. Or you can add a transition that will blank it out. Have a look at the default built-in workflow and look at "reopen" - that shows you how to do it.
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