Raye, uninstalling Structure is safe.
When you uninstall Structure plugin, the structure data (hierarchies, synchronizers, views) you've created will not be accessible, naturally. All issue data will be preserved (as if you didn't install the plugin). There are no issue fields added by Structure.
If you'd like to export the hierarchies you've created, you can use Administration | Structure | Backup Structure menu to export all data into a human-readable XML file, or use Excel export in the Structure widget.
Should you decide to install and try Structure again, the old data will be picked up (unless you also remove "structure" subdirectory in the JIRA HOME folder).
Hope this helps!
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