I also recieved following official (atlassian support) response:
As per JIRA's supported platforms page, MySQL 2008 2008 R2 is supported. Since the MS12-070 patch is supplied by Microsoft, I would not expect any issues in deploying the patch. I have never heard of any issues resulting after installing a patch, but we do not test every update released unfortunately. To be safe however, I would recommend testing this on a stage server prior to running it in production.
I did a quick search of his update and found a list of known issues related to this update:
Please be aware of these as you patch the system.
Connect with like-minded Atlassian users at free events near you!Find a group
Connect with like-minded Atlassian users at free events near you!
Unfortunately there are no AUG chapters near you at the moment.Start an AUG