If this has never worked I would first check to see that the notifcations are configured correctly. Once you verify that, I would then check the notification schemes to verify the right people/groups are assigned for the notifications you want to send.
The next step would be to check the Notifications Troubleshooting knowledge base article for further clues.
Finally, if that does not help I would check the mail logs on your outgoing SMTP server to see if that provides any further information.
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