Refreshing a issue page can be done I think, but the most important fact you need to consider is the load.
You are seeing from a issue point of view.
Assume if your project contains some 10000 issues, If all the issues refresh after 5 or 10 minutes think about the load in the server.
If you do it for all the projects then it will be a bigger problem.
As far as refeshing is concerned, I will say no, and as thomas said it is good to look into your emails as all the changes in the issue will be sent there.
Hope this helps.
I don't think that it is possible, not out of the box and more than that, not with jira on-demand. But I really think, the easiest way is to be informed via Email. If you are able to have a look at your Jira every five minutes, you can also have a look at your email client every five minutes ;-)
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