I believe you will face issues if you rearrange your backlog by the priority field. I say that, because you can only start sprints on boards that are ordered by rank (because the position of the sprint footer is stored as a ranked item). So if you order by any other field (or no field at all) the add sprint button will not be available and the board can only have one ordering (for the Sprints and for the backlog as well).
Hope this helps!
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