I'm not familiar with the Doors application but we chose JIRA because of it's flexibility and the ability for integrations with other tools as well. We use it for everything, from Requirements, SDLC, Agile, Simple Issue Tracker, Risk Management, CI/CD, Test Cases, Cooking, Parking, designing a t-shirt etc...
For a Risk Management type of project, I just created a 4 step workflow (Assess > Mitigate > Monitor > Action etc...) something like that and created custom fields which will hold key information.
For Test Cases. We started at JIRA Agile's "Epic" feature and treat is as a High Level requirement. We then use "Story" to track the work then sub-tasks type of "Test Case". This way, there will be a clear traceability and straight forward hierarchy.
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