Officially, no. It only runs on Postgres, MySQL, Oracle and MS-SQL-Server. (Also h2 and hsql, but only for dev/test instances where you don't mind losing everything)
I know of people who have run it on db2 (anything with a jdbc connector could in theory be rigged up), but it's not supported.
I have multiple projects that use variations of the same base workflow. The variations depend on the requirements of the project or issue type. The variations mostly come in the form of new statuses ...
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