You can specify a component on the create issue screen and configure the component to set an assignee different than the project lead.
Another thing you can do is a apply a post function to a workflow that changes the default assignee when issue state changes, or use something like script-runner.
I have multiple projects that use variations of the same base workflow. The variations depend on the requirements of the project or issue type. The variations mostly come in the form of new statuses ...
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