Absolutely not, you'll destroy your data. I'm assuming that you mean JIRA Server though, and not JIRA Data Centre, which will work, sort of, but then you don't need to be migrating...
You need to work with copies of the data to do this, or do the "complete shut down, move and start new system" process. See https://confluence.atlassian.com/adminjiraserver071/migrating-jira-applications-to-another-server-802592269.html
I have multiple projects that use variations of the same base workflow. The variations depend on the requirements of the project or issue type. The variations mostly come in the form of new statuses ...
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